Publications

P.L.E.A.S.E.® Research

Laser Application

Context-dependent function of TSLP and IL-1β in skin allergic sensitization and atopic march

Justine Segaud, Wenjin Yao, Pierre Marschall, François Daubeuf, Christine Lehalle, Beatriz German, Pierre Meyer, Pierre Hener, Cécile Hugel, Eric Flatter, Marine Guivarch, Laetitia Clauss, Stefan F. Martin, Mustapha Oulad-Abdelghani & Mei Li


01 September 2022, Nature Communications volume 13, Article number: 4703 (2022)

Read more

Pantec Er:YAG laser - brain surgery with vascular specific coagulation

Autor: Nitesh Katta PhD

Beckman Laser Institute

University of California in Irvine, East Irvine, Kalifornien, USA

Arnold D. Estrada PhD, Austin B. McElroy MS, Thomas E. Milner PhD

Wiley, August 10, 2022

https://doi.org/10.1002/lsm.23591

Read more

Phase I Study to Assess Safety of Laser-Assisted Topical Administration of an Anti-TNF Biologic in Patients With Chronic Plaque-Type Psoriasis
Martin Bauer, Edtih Lackner, Peter Matzellner, Valentin Al Jalali, Sahra Pajenda, Vincent Ling, Christof Böhler, Werner Braun, Reinhard Braun, Maximilian Boesch, Patrick M. Brunner, Markus Zeitlinger

Front.Med, July 16, 2021

https://doi.org/10.3389/fmed.2021.712511

Read more

Comparative ex vivo Investigations on the Cutting Quality of the CO2 Laser and the Diode Pumped Er:YAG Laser
Holger Wurm, Patrick Johannes Schuler, Florian Hausladen, René Graesslin, Thomas Karl Hoffmann, Karl Stock and Elisabeth Friederike Reins
ORIGINAL RESEARCH article, Front. Surg., 14 December 2021
Copyright 2021 Wurm, Schuler, Hausladen, Graesslin, Hoffmann, Stock and Reins. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

Read more

Laser-facilitated epicutaneous immunization of mice with SARS-CoV-2 spike protein induces antibodies inhibiting spike/ACE2 binding
Sandra Scheiblhofer, Stephan Drothler, Werner Braun, Reinhard Braun, Maximilian Bösch, Richard Weiss

Vaccine, June 26, 2021

https://doi.org/10.1016/j.vaccine.2021.06.068

Read more

Primary investigations on defined thermal effects on soft tissue using a diode pumped Er:YAG laser system
Stock K, Meitinger D, Hausladen F, Stegmayer Th, Wurm H

Proc. SPIE 10876, Optical Interactions with Tissue and Cells XXX, 108760Y (1 March 2019);

doi: 10.1117/12.2509674
Copyright 2019 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Laser facilitated epicutaneous peptide immunization using dry patch technology
Sandra Scheiblhofer, Stephan Drothler, Werner Braun, Reinhard Braun, Maximilian Bösch, Richard Weiss

bioRxiv preprint, April 28, 2021

https://doi.org/10.1101/2021.04.27.441719

Read more

Feasibility Assessment of Optical Coherence Tomography-Guided Laser Labeling in Middle Cranial Fossa Approach

Mohebbi S, Lexow J, Fuchs A, Rau Th, Tauscher S, Mirsalehi M, Hosseini S, Ortmaier T, Lenarz Th, Majdani O
Iranian Journal of Otorhinolaryngology, Volume 30, issue 6 - Serial number 101, November and December 2018, Page 321 -327
doi: 10.22038/IJORL.2018.30275.1991

Read more

Laser-assisted epicutaneous immunization to target human skin dendritic cells
Christoph H. Tripp, Hermann Voit, Angela An, Magdalene Seidl-Philipp, Johanna Krapf, Stephan Sigl, Nikolaus Romani, Barbara Del Frari, Patrizia Stoitzner

Experimental Dermatology, April 02, 2021

https://doi.org/10.1111/exd.14346

Read more

Selective removal of dental calculus with a diode-pumped Er:YAG laser
Fried W. A., Cha K. H., Darling C. L., Fried D
Proc. SPIE 104857, Lasers in Dentistry XXV, 108570M (28 February 2019)

doi: 10.1117/12.2512937
Copyright 2019 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Laser irradiation of ocular tissues to enhance drug delivery
Raghu Raj Singh Thakur, Samer Adwan, Ismaiel Tekko, Karim Soliman, Ryan F. Donnelly

Int. Journal of Pharmaceutics. 2021 March; Volume 596, 120282

doi: 10.1016/j.ijpharm.2021.120282

Read more

High efficient bone ablation with diode pumped Erbium and Thulium lasers including different delivery fibers: a comparative in vitro study
Stock K, Hausladen F, Stegmayer T, Wurm H
Proc. SPIE 10488, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII, 104880U (2018), doi:10.1117/12.2290336
Copyright 2018 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Laser-facilitated epicutaneous immunotherapy with hypoallergenic beta-glucan neoglycoconjugates suppresses lung inflammation and avoids local side effects in mouse model of allergic asthma
Evgeniia Korotchenko, Viktoria Schießl, Sandra Scheiblhofer, Mario Schubert, Elfriede Dall, Isabella A. Joubert, Helen Strandt, Theresa Neuper, Muamera Sarajilic, Renate Bauer, Mark Geppert, David Joedicke, Sabrina Wildner, Susanne Schaller, Stephan Winkler, Gabriele Gadermaier, Jutta Horejs-Hoeck, Richard Weiss

Allergy. 2021 Jan;76(1):210-222

doi: 10.1111/all.14481

Read more

High-energy diode side-pumped Er:YLF laser generating 100 mJ @ 100 Hz
Messner M, Heinrich A, Hagen C, Unterrainer K
Proc. SPIE 10511, Solid State Lasers XXVII: Technology and Devices, 105110J (2018)
doi:10.1117/12.2288134
Copyright 2018 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Laser-facilitated epicutaneous immunotherapy with depigmented house dust mite extract alleviates allergic responses in a mouse model of allergic lung inflammation
Evgeniia Korotchenko, Raquel Moya, Sandra Scheiblhofer, Isabella A. Joubert, Jutta Horejs-Hoeck, Michael Hauser, David Calzada, Victor Iraola, Jerónimo Carnés, Richard Weiss

Allergy. 2020 May;75(5):1217-1228

doi: 10.1111/all.14164

Read more

High-energy diode side-pumped Er:LiYF4 laser
Messner M, Heinrich A, Unterrainer K
Applied Optics, Vol. 57, Issue 6, pp 1497-1503 (2018)
doi:10.1364/AO.57.001497
Copyright 2018 Optical Society of America

Read more

Dual function of Langerhans cells in skin TSLP-promoted Tfh cell differentiation in mouse atopic dermatitis
Pierre Marschall, Ruicheng Wei, Justine Segaud, Wenjin Yao, Pierre Hener, Beatriz Falcon German, Pierre Meyer, Cecile Hugel, Grace Ada Da Silva, Reinhard Braun, Daniel H Kaplan, Mei Li

J Allergy Clin Immunol, 2020 Oct 14; S0091-6749(20)31408-1

doi: 10.1016/j.jaci.2020.10.006

Read more

Seeing laser scalpel: a novel monolithic high-power diode pumped Tm:YAG laser system at 2.02 µm with double-clad fiber combined OCT
Messner M, Heinrich A, Hagen C, Unterrainer K
Proc. SPIE 10054, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XV, 100540X (February 14,2017), doi:10.1117/12.2250779
Copyright 2017 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Targeted cutaneous delivery of etanercept using Er:YAG fractional laser ablation
del Río Sancho S, Lapteva M, Sonaje K, Böhler C, Ling V, Boehncke W, Kalia Y

International Journal of Pharmaceutics, Volume 580, 30 April 2020

doi: 10.1016/j.ijpharm.2020.119234

Read more

Investigations on the potential of a novel diode pumped Er:YAG laser system at high mean laser power for hard tissue preparation in dentistry
Hausladen F, Wurm H, R Hibst, K Stock
Proc. SPIE 10044, Lasers in Dentistry XXIII, 100440B (February 10,2017)
doi:10.1117/12.2252921
Copyright 2017 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Epidermal micro-perforation potentiates the efficacy of epicutaneous vaccination
Hervé P, Dhelft V, Plaquet C, Rosseaux A, Bouzereau A, Gaulme L, Tilleul S, Ligouis M, Donne N, Lambert P, Hong-Thai P, Wijagkanalan W, Sampson H A, Mondoulet L

Journal of Controlled Release, Volume 298, 28 March 2019, Pages 12-26

doi: 10.1016/j.jconrel.2019.02.004

Read more

Selective removal of natural caries lesions from dentin and tooth occlusal surfaces using a diode-pumped Er:YAG laser

Jew J., Chan K.H., Darling C.L., Fried D.

Proc. SPIE 10044, Lasers in Dentistry XXIII, 100440I (February 8,2017)
doi:10.1117/12.2256728

Copyright 2017 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Fractional laser ablation for the targeted cutaneous delivery of an anti-CD29 monoclonal antibody - OS2966
Lapteva M, del Río Sancho S, Wu E, Carbonell WS, Böhler C, Kalia YN

Sci Rep. 2019 Jan 31; 9(1):1030. doi: 10.1038/s41598-018-36966-0

Read more

Influence of multi-wavelength laser irradiation of enamel and dentin surfaces on surface morphology and permeability

Chang NY.N., Jew J., Simon J.C., Chan K.H., Lee R.C., Fried W.A., Cho J., Darling C.L., Fried D.Proc. SPIE 10044, Lasers in Dentistry XXIII, 100440H (February 8,2017), doi:10.1117/12.2256734

Copyright 2017 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Parameters in fractional laser assisted delivery of topical anesthetics: Role of laser type and laser settings.
Meesters AA, Nieboer MJ, Kezic S, de Rie MA, Wolkerstorfer A

Lasers Surg Med, 2018 May 7; doi: 10.1002/lsm.22936

Read more

Selective removal of dental composite with a diode-pumped Er:YAG laser

William A. Fried, Kenneth H. Chan, Cynthia L. Darling, Daniel Fried

Proc. SPIE Int Soc Opt Eng. 2016 Feb 9692: 96920S , doi:10.1117/12.2218645

Copyright 2016 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Lack of dermal penetration of topically applied gentamicin as pharmacokinetic evidence indicating insufficient efficacy.
Oesterreicher Z, Lackner E, Jäger W, Höferl M, Zeitlinger M

J Antimicrob Chemother, 2018 Aug 2; doi: 10.1093/jac/dky274

Read more

High brightness diode pumped Er:YAG laser system at 2.94 µm with nearly 1 kW peak power

Manuel Messner, Arne Heinrich, Clemens Hagen, Karl Unterrainer

Proc. SPIE 9726, Solid State Lasers XXV: Technology and Devices, 972602 (March 17, 2016)
doi:10.1117/12.2209098

Copyright 2016 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Needle-free cutaneous delivery of living human cells by Er:YAG fractional laser ablation.
Yu J, Dubey S, Kalia YN

Expert Opin Drug Deliv. 2018 Jun;15(6):559-566. doi: 10.1080/17425247.2018.1472570

Read more

Endoluminal non-contact soft tissue ablation using fiber-based Er:YAG laser delivery

Dennis Kundrat, Alexander Fuchs, Andreas Schoob, Lüder A. Kahrs, Tobias Ortmaier

Proc. SPIE 9702, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVI, 97020E (March 7, 2016) , doi:10.1117/12.2211796

Copyright 2016 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Application of water-soluble polyvinyl alcohol-based film patches on laser microporated skin facilitates intradermal macromolecule and nanoparticle delivery.
Engelke L, Winter G, Engert J

Eur J Pharm Biopharm, 2018 Juli;128:119-130. doi: 10.1016/j.ejpb.2018.04.008

Read more

Primary investigations on the potential of a novel diode pumped Er:YAG laser system for middle ear surgery

Karl Stock, Holger Wurm, Florian Hausladen

Proc. SPIE 9689, Photonic Therapeutics and Diagnostics XII, 96892K (March 1, 2016)
doi:10.1117/12.2213105

Copyright 2016 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Delivery of Methotrexate and Characterization of Skin Treated by Fabricated PLGA Microneedles and Fractional Ablative Laser.
Nguyen HX, Banga AK

Pharm Res, 2018 Feb, 21;35(3):68. doi: 10.1007/s11095-2369-6

Read more

Mass Spectrometry of Levitated Droplets by Thermally Unconfined Infrared-Laser Desorption

Carsten Warschat, Arne Stindt, Ulrich Panne, Jens Riedel

Analytical Chemistry, 2015, 87 (16), pp 8323–8327 (August 3, 2015)
doi:10.1021/acs.analchem.5b01495

Copyright © 2015 American Chemical Society

Read more

Qualitative and quantitative analysis of lateral diffusion of drugs in human skin.
Nguyen HX, Puri A, Bhattaccharjee SA, Banga AK

Int J Pharm, 2018 Jun 10; 544(1):62-74, doi: 10.1016/j.ijpharm.2018.04.013

Read more

Fast and automatic depth control of iterative bone ablation based on optical coherence tomography data

Alexander Fuchs, Steffen Pengel, Jan Bergmeier, Lüder A. Kahrs, Tobias Ortmaier

Proc. SPIE 9542, Medical Laser Applications and Laser-Tissue Interactions VII (15 July 2015)
doi:10.1117/12.2183695

Copyright 2015 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Transdermal delivery of human growth hormone via laser-generated micropores.
Yang Song, Karishma Hemmady, Ashana Puri, Ajay K. Banga

Drug Deliv Transl Res., 2018 Apr; 8(2):450-460, doi: 10.1007/s13346-017-0370-y

Read more

Efficient bone cutting with the novel diode pumped Er:YAG laser system: in vitro investigation and optimization of the treatment parameters

Stock K, Diebolder R, Hausladen F, Hibst R
Proc. SPIE 8926, Photonic Therapeutics and Diagnostics X, 89263P (March 4, 2014)
doi:10.1117/12.2039648

Copyright 2014 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy.
Machado Y, Duinkerken S, Hoepflinger V, Mayr M, Korotchenko E, Kurtaj A, Pablos I, Steiner M, Stoecklinger A, Lübbers J, Schmid M, Ritter U, Scheiblhofer S, Ablinger M, Wally V, Hochmann S, Raninger AM, Strunk D, van Kooyk Y, Thalhamer J, Weiss R

J Control Release, 2017 Sep 14; 266:87-99, doi: 10.1016/j.conrel.2017.09.020

Read more

Investigations on the potentail of a low power diode pumped Er:YAG laser system for oral surgery

Stock K, Diebolder R, Hausladen F, Hibst R
Proc. SPIE 9306, Lasers in Dentistry XXI, 930605 (February 24, 2015)
doi:10.1117/12.2078723

Copyright 2015 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Skin vaccination via fractional infrared laser ablation - Optimization of laser-parameters and adjuvantation
S Scheiblhofer, A Strobl, V Hoepflinger, T Thalhamer, M Steiner, J Thalhamer, R Weiss

Vaccine, Jan. 2017, pii: S0264-410X(17)30058-0, DOI:10.1016/j.vaccine.2016.11.105, PMID: 28117172

Read more

Aplanatic beam shaping for diffraction limited beam circularization of tapered laser diodes

Heinrich A, Hagen C, Harlander M, Nussbaumer B
Proc. SPIE 8965, High-Power Diode Laser Technology and Applications XII, 89650W (March 7, 2014)
doi:10.1117/12.2039355

Copyright 2014 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Potential of nanoparticles for allergen-specific immunotherapy - use of silica nanoparticles as vaccination platform
S Scheiblhofer, Y Machado, A Feinle, J Thalhamer, N Hüsing, R Weiss

Expert Opinion on Drug Delivery, Dec. 2016, 13(12):1777-1788, DOI:10.1080/17425247.2016.1203898, PMID: 27321476

Read more

High brightness diode pumped Er:YAG laser system at 2.94 µm with 400W peak power

Harlander M, Heinrich A, Hagen C, Nussbaumer B
Proc. SPIE 8959, Solid State Lasers XXIII: Technology and Devices, 895908 (February 28, 2014)
doi:10.1117/12.2037746

Copyright 2014 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Laser-facilitated epicutaneous immunotherapy to IgE-mediated allergy
MN Kumar, C Zhou, MX Wu

Journal of Controlled Release, Aug. 2016, 235:82-90, DOI:10.1016/j.conrel.2016.05.057, PMID: 27235977

Read more

Automatisierte Überwachung der Laserosteotomie mittels optischer Kohärenztomographie

Fuchs A, Kundrat D, Schultz M, Krüger A, Ortmaier T
Publication Date: 2012.11.15
Best Paper Award - CURAC - Deutsche Gesellschaft für Computer- und Roboterassistierte Chirurgie e.V.

>> For more information please contact 3um@pantec.com

Fractional Laser Ablation for the Cutaneous Delivery of Triamcinolone Acetonide from Cryomilled Polymeric Microparticles: Creating Intraepidermal Drug Depots
M Singhal, S Del Rio-Sancho, K Sonaje, YN Kalia

Mol Pharm, Feb. 2016;13(2):500-11, DOI:10.1021/acs.molpharmaceut.5b00711, PMID: 26731121

Read more

Investigations on the potential of a novel diode pumped Er:YAG laser system for dental applications

Stock K, Hausladen F, Hibst R
Proc. SPIE 8208, Lasers in Dentistry XVIII, 82080D (February 9, 2012)
doi:10.1117/12.908382

Copyright 2012 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Ablative fractional laser enhances MAL-induced PpIX accumulation: Impact of laser channel density, incubation time and drug concentration
C.S. Haak, K. Christiansen, A.M. Erlendsson, E.H. Taudorf, D. Thaysen-Petersen, H.C. Wulf, M. Haedersdal

Journal of Photochemistry & Photobiology, B: Biology, June 2016, 159:42-8, DOI:10.1016/j.iphotobiol.2016.03.021

Read more

Using laser microporation to improve transdermal delivery of diclofenac: Increasing bioavailability and the range of therapeutic applications.

Bachhav YG, Heinrich A, Kalia YN.
Eur J Pharm Biopharm. 2011 Aug; 78(3):408-14. Epub 2011 Mar 21.
PMID: 21397689

Read more

Practical approach to the use of daylight photodynamic therapy with topical methyl aminolevulinate for actinic keratosis: a European consensus
Morton CA, Wulf HC, Szeimies RM, Gilaberte Y, Basset-Sequin N, Sotiriou E, Piaseriao S, Hunger RE, Baharlou S, Sidoroff A, Braathen LR

J Eur Acad Dermatol Venerol, Sept. 2015;29(9):1718-23, DOI:10.1111/jdv.12974, PMID: 25627399

Read more

High-power, diode-pumped Er:YAG lasers for soft and hard tissue applications

Heinrich A, Hagen C, Vizhanyo A, Krammer P, Summer S, Gross S, Boehler C, Bragagna T.
Proc. SPIE 8092, Medical Laser Applications and Laser-Tissue Interactions V, 80921C (June 02, 2011)
doi:10.1117/12.888255

Copyright 2011 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Ablative fractional laser alters biodistribution of ingenol mebutate in the skin
A.M. Erlendsson, E.H. Taudorf, A.H. Eriksson, C.S. Haak, J.R. Zibert, U. Paasch, R.R. Anderson, M. Haedersdal

Arch Dermatol Res, Aug. 2015,;307(6):515:-22, DOI:10.1007/s00403-015-1561, PMID:25832754

Read more

30 mJ, TEM00, high repetition rate, mechanically Q-switched Er:YAG laser operating at 2940 nm

Skorczakowski M, Pichola W, Swiderski J, Nyga P, Galecki L, Maciejewska M, Zajac A, Gross S, Heinrich A, Bragagna T, Kasprzak J.
Opto-Electronics Review, Volume 19, Issue 2, pp.206-210
DOI: 10.2478/s11772-011-0011-9

Read more

Laser-Assisted Intradermal Delivery of Adjuvant-Free Vaccines Targeting XCR1+ Denditric Cells Induces Potent Antitumoral Responses
D. Terhorst, E. Fossum, A Baranska, S. Tamoutounour, C. Malosse, M. Garbani, R. Braun, E. Lechat, R. Crameri, B. Bogen, S. Henri, B. Malissen

The Journal of Immunology, May 2015, DOI:10.4049/jimmunol.1500564

Read more

High power, diode side pumped Er:YAG lasers

Heinrich A, Bragagna T.
Lasers and Electro-Optics Europe (CLEO EUROPE/EQEC), 2011 Conference and 12th European Quantum Electronics Conference
Issue Date: 22-26 May 2011 On page(s): 1 - 1, Location: Munich, ISSN: Pending
Print ISBN: 978-1-4577-0533-5
INSPEC Accession Number: 12189945
Digital Object Identifier: 10.1109/CLEOE.2011.5942493
Date of Current Version: 07 Juli 2011

Read more

Combination of ablative fractional laser and daylight-mediated photodynamic therapy for actinic keratosis in organ transplant recipients - a randomized controlled trial
K. Togsverd-Bo, U. Lei, A.M. Erlendsson, E.H. Taudorf, P.A. Philipsen, H.C. Wulf, L. Skov and M. Haedersdal

British Journal of Dermatology, Feb. 2015, DOI:10.1111/bjd.13222, PMID: 24975199

Read more

Next generation Er:YAG fractional ablative laser

Heinrich A, Hagen C, Vizhanyo A, Krammer P, Summer S, Gross S, Bragagna T, Boehler C.
Proc. SPIE 7883, Photonic Therapeutics and Diagnostics VII, 78830M (February 17, 2011)
doi:10.1117/12.873522

Copyright 2011 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

The origins and functions of dendritic cells and macrophages in the skin
B Malissen, S Tamoutounour, S Henri

Nat Rev Immunol, June 2014;14(6):417-28, DOI:10.1038/nri3683, PMID: 24854591

Read more

High power, diode pumped Er:YAG for dentistry

Hagen C, Heinrich A, Nussbaumer B
Proc. SPIE 7884, Lasers in Dentistry XVII, 78840I (February 17, 2011) , doi:10.1117/12.873549

Copyright 2011 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Miniaturized high power Er:YAG solid state laser pumped by a single laser diode bar

Krejci M, Heinrich A, Mueller J, Bragagna T, Lichtenstein N.
Proc. SPIE 7912, Solid State Lasers XX: Technology and Devices, 79121D (February 15, 2011)
doi:10.1117/12.873576

Copyright 2011 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Read more

Next generation intra- and transdermal therapeutic systems: Using non- and minimally-invasive technologies to increase drug delivery into and across the skin
T Gratieri, I Alberti, M Lapteva, YN Kalia

European Journal of Pharmaceuticical Sciences, Dec. 2013; 50(5):609-22, DOI:10.1016/j.ejps.2013.03.019, PMID: 23567467

Read more

Using controlled laser-microporation to increase transdermal delivery of prednisone.

Yu J, Bachhav YG, Summer S, Heinrich A, Bragagna T, Boehler C, Kalia YN.
J Control Release. 2010 Nov 20; 148(1):e71-3. No abstract available.
PMID: 21529638

Read more

Controlled intra- and transdermal protein delivery using a minimally invasive Erbium:YAG fractional laser ablation technology
YG Bachhav, A Heinrich, YN Kalia

European Journal of Pharmaceutics and Biopharmaceutics, June 2013; 84(2):355-64, DOI:10.1016/j.ejpb.201211.018, PMID: 23207321

Read more

Effect of controlled laser microporation on drug transport kinetics into and across the skin.

Bachhav YG, Summer S, Heinrich A, Bragagna T, Boehler C, Kalia YN.
J Control Release. 2010 Aug 17; 146(1):31-6. Epub 2010 May 25.
PMID: 20678988

Read more

Laser microporation of the skin: prospects for painless application of protective and therapeutic vaccines
S Scheiblhofer, J Thalhamer, R Weiss

Expert Opinion Drug Delivery, June 2013; 10(6):761-73, DOI:10.1517/17425247.2013.773970, PMID: 23425032

Read more

Mid-infrared Q-switched Er:YAG laser for medical applications

Skorczakowski M, Swiderski J, Pichola W, Nyga P, Zajac A, Maciejewska M, Galecki L, Kasprzak J, Gross S, Heinrich A, Bragagna T.
 Publication date: 2010.01.07
Laser Physics Letters
DOI: 10.1002/lapl.201010019

Read more

Transcutaneous immunotherapy via laser-generated micropores efficiently alleviates allergic asthma in Phl p 5-sensitized mice
D. Bach, R. Weiss, M. Hessenberger, S. Kitzmueller, E.E. Weinberger, W.D. Krautgartner, C. Hauser-Kronberger, C. Boehler, J. Thalhamer, S. Scheiblhofer

European Journal of Allergy and Clinical Immunology,  Nov 2012; 67(11): 1365-1374, DOI: 10.1111/all.12005

Read more

Transcutaneous vaccination via laser microporation
R. Weiss, M. Hessenberger, S. Kitzmueller, D. Bach, E.E. Weinberger, W.D. Krautgartner, C. Hauser-Kronberger, B. Malissen, C. Boehler, Y.N. Kalia, J.Thalhamer, S. Scheiblhofer

J Control Release 2012. September 2012; 162(2): 391-399

Read more

Erbium:YAG fractional laser ablation for the percutaneous delivery of intact functional therapeutic antibodies
J Yu, DR Kalaria, YN Kalia

J Control Release, Nov. 2011; 156(1):53-9, DOI: 10.1016/j.conrel.2011.04.024, PMID: 21803083

Read more

Using laser microporation to improve transdermal delivery of diclofenac: Increasing bioavailability and the range of therapeutic applications.
Bachhav YG, Heinrich A, Kalia YN.
Eur J Pharm Biopharm. 2011 Aug; 78(3):408-14. Epub 2011 Mar 21.
PMID: 21397689

Read more

High power, diode side pumped Er:YAG lasers
Heinrich A, Bragagna T.
Lasers and Electro-Optics Europe (CLEO EUROPE/EQEC), 2011 Conference and 12th European Quantum Electronics Conference
Issue Date: 22-26 May 2011
On page(s): 1 - 1
Location: Munich
ISSN: Pending
Print ISBN: 978-1-4577-0533-5
INSPEC Accession Number: 12189945
Digital Object Identifier: 10.1109/CLEOE.2011.5942493
Date of Current Version: 07 Juli 2011

Read more

Using controlled laser-microporation to increase transdermal delivery of prednisone.
Yu J, Bachhav YG, Summer S, Heinrich A, Bragagna T, Boehler C, Kalia YN.
J Control Release. 2010 Nov 20; 148(1):e71-3. No abstract available.
PMID: 21529638

Read more

Effect of controlled laser microporation on drug transport kinetics into and across the skin.
Bachhav YG, Summer S, Heinrich A, Bragagna T, Boehler C, Kalia YN.

J Control Release. 2010 Aug 17; 146(1):31-6. Epub 2010 May 25.
PMID: 20678988

Read more

Noninvasive Transdermal Iontophoretic Delivery of Biologically Active Human Basic Fibroblast Growth Factor
S. Dubey, R. Perozzo, L. Scapozza, YN Kalia
Molecular Pharmaceutics Aug. 2011; 8(4):1322-31, DOI: 10.1021/mp200125j, PMID: 21696184

Read more

Development and validation of an analytical method for the quantification of cytochrome c in skin transport studies
YG. Bachhav, YN. Kalia

Biomedical Chromatography, July 2010, 24(7):732-6, DOI:10.1002/bmc 1356

Read more

Mid-infrared Q-switched Er:YAG laser for medical applications
Skorczakowski M, Swiderski J, Pichola W, Nyga P, Zajac A, Maciejewska M, Galecki L, Kasprzak J, Gross S, Heinrich A, Bragagna T.
Publication date: 2010.01.07
Laser Physics Letters
DOI: 10.1002/lapl.201010019

Read more